Who Is an Entrepreneur

Common/different aspects of the paper2 Conclusions6 References7 â€Å"Who is an entrepreneur? † Introduction â€Å"Who is an entrepreneur? † is a question that aroused many controversies and debates. Among many articles that talks about the entrepreneur and the process of entrepreneurship I will focus on three articles that tried to answer this question or demonstrated the uselessness of the question. Analyzing many different points of view will conduct to a better and deeper understanding of the phenomena.Therefore, this is not an exact science, like for instance mathematics or physics. It leads us more to interpretation, which means that, there will always be a need of debate. Short Summary In the article â€Å"Differentiating Entrepreneurs from Small Business Owners: A Conceptualization†, Carland et al. tries to answer the question by focusing on the characteristics of an entrepreneur and they go further with comparing him to a small business owner. They settl e a definition for each and then, they apply the main ideas to a larger scale and differentiate an entrepreneurial venture from a small business.Gartner criticize their point of view in his article â€Å"Who is an entrepreneur? Is the wrong question† and considers that it is improper to define â€Å"the entrepreneur† because it would mean that an entrepreneur fits a certain type of person, which is not true since the views are not homogenous. That is why Gartner considers a more suitable approach for the concept, to analyze the entrepreneur’s behavior. In the article â€Å"Who is an entrepreneur? Is a question worth asking†, Carland et al. tries to respond to Gartner’s critique and in the end, he argues that indeed entrepreneurship is a complex and dynamic concept.Common/different aspects of the paper In the article â€Å"Differentiating Entrepreneurs from Small Business Owners: A Conceptualization†, Carland et al. , in terms of entrepreneur and small business owner, focus on intentionality and characteristics. In their opinion, an entrepreneur’ purpose is profit and growth and he is characterized as an innovative person who will employ strategic management practices, while a small business owner’s purpose is furthering personal goals, and to whom the business is the primary source of income which will consume almost all of his time.In terms of differentiating Entrepreneurial Ventures form Small Business Ventures, they focus on the same ideas applied to a bigger scale. However, this attempt to define the concepts, and especially their arguments were hardly criticized by Gartner in his article â€Å"Who Is an Entrepreneur? Is the Wrong Question†. He brings into discussion the situation when â€Å"an individual personal goal is to establish a business for profit and growth†. He considers that Carland et al. are rung, first by focusing on intentionality, instead of creation, and second by focus ing on the person instead of the act of entrepreneurship.He argues that, by referring only to intentionality rather than to concrete things like articulated strategies or observed behaviors, they increased even more the ambiguity. In my opinion, Carland et al. ’s attempt to define a small business owner as an individual whose main characteristic is achieving its personal goals is a vague statement. To be more specific, I will take as an example a farmer, who lives in the country, has no job, owns 10 hectares of vineyards, and decides to start a business in wine industry. For him, this will be the primary source of income.To help me set his goals, I will analyze Maslow pyramid. According to Abraham Maslow we will start from the base. Our farmer’s first goal will be to sell as much wine as to be able to sustain his physiological needs, like buying food, water and so one. After satisfying his basic needs, he will want to assure the need of safety and therefore, he will ne ed to earn more money. So how can he do that? Growing his business and raising his earnings. This means that his goal will change into growth and profit while his business remains his principal source of income. And so one, we can continue to higher stages in the pyramid.Therefore, I consider that, the desire of achieving its personal goals cannot be a specific characteristic for a small business owner. I also believe that the two terms, â€Å"entrepreneur† and â€Å"small business owner†, are so close related that the transition between them can be made very easy and therefore I again disagree with Carland et al. because of their attempt to totally separate the concepts. For instance, if we take the farmer, on the the first stage of Maslow pyramid, according to Carland et al. , he fits the description of a small business owner, by having his business as his primary source of income and furthering his personal goals.But, what if we add that he discovers a secret recipe of wine, a new type of product, and he is able to put it into practice? This last feature belongs to an entrepreneur; therefore, the farmer will have both characteristics from a small business owner and an entrepreneur. So is he really a small business owner or he had become an entrepreneur? Gartner tries to show what differentiates an entrepreneur from non-entrepreneurs and it demonstrates that behavioral approaches are the ones we should concentrate on, for analyzing future researches in entrepreneurship, than trait approaches.He also recognizes that trait approaches and behavioral trait approaches are two related concepts that cannot be treated separately. Gartner explains that if we talk about behavioral and trait approaches, we analyze the entrepreneur’s characteristics through its activities undertaken to create an organization. For instance, Arthur Cole tries to take a behavioral viewpoint of an entrepreneur and then analyses his traits and specific characteristics (j udgment, perseverance, knowledge of the world and business).Jenks and Kilby disagree with studying the personality of an entrepreneur and they encourage researchers to study the behaviors and activities of an entrepreneur. However here, I consider that we can analyze equally, both the traits and the behavioral of an individual, because are strongly connected, and can be related in both ways, but the focus should be on the behavior. First, the behavior of an individual can be determined by its characteristics, as if for instance a person who most often takes hasty decisions he could be an impulsive person.And second, if we analyze an individual characteristics, we can suppose that he will behave in a certain way, like if he is very confident in its believes he could assume more risks than a person who does not trust its own ideas. Still we have to analyze each person as a simple, because everyone is unique and behaves in its own way. Gartner uses researches that focuses on the person of the entrepreneur, and tries to settle an entrepreneur’s qualities (traits), like: need for achievement, locus of control, risk taking, values, age, and others.Then he explains that these are worthless to differentiate entrepreneurs from others, because in the trait approach, an entrepreneur is considered a particular personality type with certain characteristics, but if we look at the studies, we can see that few entrepreneurs employ the same definition, so the views are not homogenous. In the article â€Å"Who is an entrepreneur? Is a question worth asking†, after analyzing a compilation of Gartner’s studies of entrepreneurship, Carl et al. demonstrated the fruitlessness of his trait research.They considered that he used inconsistent definitions, samples that are not homogeneous or comparable and most important, he created an inconsistent entrepreneurial profile, which is often not significantly different from the rest of the population. Van de Ven finds it also important to analyze the traits and characteristics of a leader. However, Carland et al. considered that there are not so many classification schemes involving complex human behavior and that is one reason why they have excluded it.According to Gartner, we cannot talk anymore about â€Å"entrepreneurs† in general without referring to characteristics of the sample. In their continuous attempt to separate the term of â€Å"entrepreneur† from â€Å"small business owner† Carland et al. uses also psychology literature and considers that one’s personality is defined by all aspects of life and is largely set during the formative years. However, Gartner still believes that it is impossible to settle certain traits for an entrepreneur because everyone is different from other.Gartner also disagrees with the last part of Carland et al. entrepreneurial definition, which ties the state of being an entrepreneur to innovative behavior, and he brings up the problem of identifying if only the first firms in each industry are the innovative ones and all other subsequent would be small business owners. I consider that an entrepreneur is an innovative person, so in this respect I disagree with Gartner’s opinion. In addition, this does not mean that only the first company in each industry is innovative, like Gartner believes.Even if two firms are competing on the same industry, the second firm appeared on the market, could have products with the same utility and some similar characteristics, but the product can also contain an extra new, special, different, and innovative characteristic. Like for instance when it appeared the beer with lemon, I consider that is was a result of innovative thinking, because although it has the main utility of a bear, to quench the thirst, and has similar characteristics, it can also be seen as a new and different product.In this respect, Bhide, in his article â€Å"The questions every entrepreneur must answe r†, considers that in the same industry, the option that suits for one entrepreneurial venture can be completely inappropriate for another. In addition, he gives as an example companies like Microsoft, Lotus, WordPerfect, and Intuit, which are competing in the same industry but had a very different evolution. In his research â€Å"What is entrepreneurship? , Davidsson analyzes entrepreneurship through competitive behaviors. He agrees with Gartner. He does not consider innovation as an example of entrepreneurship. On the one side, he manages to avoid more the risk of ambiguity by restricting the entrepreneurship concept to a market context which gives a more precise characterization to the process and on the other its permissive because it has no restriction to innovation, organizational context, risk taking and others.He sees entrepreneurship on a small level, which has important effects on a bigger scale, because it influences the whole market. In addition, it is brought int o discussion the problem of differentiating a product from its similar product that constitutes innovation. Moreover, but not lastly we confront with the dilemma if new methods of manufacturing, marketing, distributing the product could be also considered as innovation and here, Gartner brings into discussion, the debate on which are the truly innovative methods.In the end, Gartner tries to change a long held viewpoint of entrepreneurial process by identifying it as the creation of new organizations. After that, he debates if the entrepreneurship ends once the organization creation is over. In his opinion the entrepreneurship ends once with the creation stage of the organization. In these respect, Greiner (1972) and Steinmetz (1969) considers that any organization can survive on past its creation stage to all the possible stages like growth, maturity, and decline.Therefore, if we look at the process itself and analyze each stage, when the individual creates an organization he takes different roles like innovator, manager, small business owner and many others and each is characterized by specific behaviors. But the order of these stages aren’t always the same. I consider that when the creation of the organization is on its end stage, we cannot say that entrepreneurial process it’s necessarily over. In certain situations, some firms extend their business by discovering a new revolutionary product.To be more specific, if we take in consideration a company which produces milk, and it discovers a new product that haven’t existed before, let’s suppose it’s butter, than the company will have to develop only some extra operations to make the revolutionary product. Therefore, the milk company will support a creation of a new sub organization in this section (technology, marketing, sales, management, and so one). Moreover, here come into discussion the habitual entrepreneurs, who, after creating a business, they are still identifying n ew business opportunities and put it into practice when they are able to do that.An interesting polemics, we can find on the article of Ucbasaran et al. , â€Å"Does entrepreneurial experience influence opportunity identification? †. After using data and research methodology among individuals engaged in entrepreneurial acts, they conclude that, on the one side, there are some differences between inexperienced novice entrepreneurs and experienced habitual entrepreneurs, but on the other, they also have some similarities in their behavior.Both habitual and novice entrepreneurs are in continuous searching for knowledge and development. One difference between these two categories is that with their experience, habitual entrepreneurs, identify more business opportunities, and one explanation could be that they use different sources of information like financiers, employees, and consultants. In addition, their attitude to business opportunity identification is different. They consi der that one opportunity often leads to another but it can also emerge in connection with some problems.Experienced entrepreneurs are also convinced that it is crucial to obtain the necessary resources and capital to implement a good idea, and they underline the importance of spontaneity and alertness. In addition, experienced entrepreneurs often identify business opportunities with higher level of innovativeness. One explication could be their ability of choosing the best person for the right activity, based on their experience, which gives them more time to develop more business opportunities. Wright et al. brings into discussion the risk of habitual entrepreneurs to repeat same ideas but in different or changed environments.I believe that habitual entrepreneurs indeed find more easily business opportunities because of their experience in the changing of the market needs, and most important customer’s needs. They have a better understanding of the market mechanism and how v ital is the spontaneity. They also understand better the consequences of doing or not doing something. However, entrepreneurship cannot be treated as an independently concept so therefore it can be related to areas like for instance mathematics, statistics, economics and many others.We find an attempt to prove the importance of having a complex model, in Bygrave and Hofer’s research, â€Å"Theorizing about Entrepreneurship†, where they try to highlight that entrepreneurship is a dynamic concept, which can’t be analyzed very good, using simples models like regression. They consider that we need a model with much more variables, such as: discontinuities in entrepreneurial process, changes of state (changes of phase in organization, including start-ups), sensitivity to initial conditions and multiplicity to anterior variables.In my opinion, using mathematics or some other exact sciences offers us a less subjective approach but if the model is not complex enough, we can also miss some details that could lead us to a rung conclusion or interpretation. Conclusions After analyzing opinions from several authors of articles, who tried to understand the concept of entrepreneurship and â€Å"Who is an entrepreneur? †, we can conclude that there are many points of view in this respect and that’s why we cannot reach to a general valid and accepted definition of the concepts.Some tried to establish the differences between entrepreneurs and non-entrepreneurs, others tried to differentiate even the entrepreneurs between them, focusing on experience, and some tried to measure the concept through statistics, all having the same aim, to understand deeper the concept. However, there will always be the need of debate because the concept itself is a subjective one. So it remains to our discretion what opinion do we agree with, or we may very well create our own concept of an entrepreneur and entrepreneurship.In my opinion, a better understanding o f the entrepreneur concept, needs a more suitable question, than â€Å"Who is an entrepreneur? †, like â€Å"What does an entrepreneur do? †. I believe that if we are able to establish his behavior, this will lead us to its characteristics, on the one side, and on the other, it could also give us a vision of his potential future behavior. After analyzing all points of view, I finally created my own concept of an entrepreneur.Therefore, first I believe that an entrepreneur should be able to create an organization, based on an original innovative idea, and sustain it. Second, he is concentrated on anticipating the need of the person on long term and finds the most efficient way of satisfying it. Third, he takes huge risks in order to fulfill its goal and he is able to adapt easy to changes. Moreover, most of all he identifies itself with the organization. Therefore, on an entrepreneur all these characteristics and behaviors complement each other.References Bhide, A. 1996 ) The question every entrepreneur must answer, Harvard Business Review, 74(6), 120-130 Bygrave, W. D. & Hofer, C. W. (1991), Theorizing about entrepreneurship, Entrepreneurship Theory an Practice, 16(2), pp. 13-39 Carland, J. W. , Hoy, F. , Boulton, W. R. , & Carland, J. A. (1984). Differentiating entrepreneurs from small business owners: A conceptualization.Academy of Management Review, 9(2), 354-359 Carland, J. W. , Hoy, F. , & Carland, J. A. C. (1988): _’Who is an Entrepreneur? _Is a question worth asking’, American Journal of Small Business, 12(4): p. 3-39. Davidsson, P. (2004) What is entrepreneurship? Chapter in Researching entrepreneurship. Boston, Massachusetts: Springer. Gartner, W. (1989)

Genetic Testing For Haemophilia Health And Social Care Essay

MFA presented to the day care of the Paediatric section with left mortise joint swelling for one twenty-four hours after hitting his mortise joint on a rock while playing in the flushing one twenty-four hours prior to admittance. There was hurting and bruising seen at the mortise joint articulation after the injury. The swelling increased in size and became more painful throughout the dark. His parents so brought him to the day care early the following forenoon. Physical scrutiny revealed swelling and tenderness at the left ankle joint every bit good as decreased scope of motion on both inactive and active motion due to trouble. There were besides multiple ecchymosis in different phases seen at the upper and lower limbs. A diagnosing of haemarthroses of the left mortise joint articulation was made. MFA was transfused with 200IU of Factor VIII. The hurting and puffiness were reduced in badness but persisted throughout the twenty-four hours. MFA returned to the day care the following twenty-four hours for more Factor VIII. He was given Factor VIII transfusion 200 IU twice daily for the following two yearss. The hurting and puffiness subsided after 3 yearss. MFA was diagnosed with terrible Haemophilia Angstrom when he was eight months of age. The diagnosing was made at the national blood bank. Familial testing besides done at the national blood bank revealed that his female parent was a haemophilia cistron bearer. MFA receives transfusion of Factor VIII when he develops haemarthroses or shed blooding due to trauma. He requires factor transfusion on an norm of one time every three months. He has had repeated hospital admittances with an mean continuance of stay for three to four yearss. MFA has good household support and is a member of the haemophilia society. He and his household have adapted good to his unwellness. Student Name: Tan Hai Liang ID NO: M0409146 Name OF SUPERVISOR: Dr Kyin ROTATION: PediatricssPATIENT ‘S DETAILSI/C NUMBER: ( B ) 630902-01-6092 Age: 9 old ages old Sexual activity: Male DATE OF ADMISSION: 23/04/09 R/N NUMBER: N/A2 ) CLINICAL HISTORYChief ailment: MFA is a nine twelvemonth old male child who was diagnosed with haemophilia A since eight months old. He presented with swelling in the left mortise joint for one twenty-four hours. History of present unwellness: MFA was running in the field at school when he knocked his mortise joint against a big rock in the land on the eventide of the twenty-four hours prior to showing at the day care. There was hurting after he hit his mortise joint but he was able to bear weight and walk. There was some bruising but no hemorrhage at the site of hurt. The joint became more painful towards the dark and there was some puffiness, heat and inflammation which increasingly increased. The hurting increased in badness so much so that MFA was unable to bear weight and used a wheelchair belonging to his brother to travel about the house. The hurting caused him some uncomfortableness but he was able to kip. He did non take any analgesia for the hurting. The following twenty-four hours, MFA ‘s parents brought him to the day care of the pediatric section for a factor transfusion. Systemic reappraisal was everyday. MFA was foremost diagnosed with haemophilia A when he was 8 months of age. His parents noticed that he developed contusions at his custodies and articulatio genuss. This occurred when he was tilting to creep. A blood trial was done in the national blood bank, and his parents were told that MFA had terrible hemophilia A. His immediate household underwent testing and his female parent was found to be a bearer of the haemophilia cistron. MFA receives factor VIII transfusion on an norm of one time every three months. The transfusions are required when he develops haemarthroses or gum hemorrhage due to tooth decay. The joint most normally affected is his right articulatio genus articulation. He has non developed any contractures. He does non normally seek medical intervention for contusions which are a common happening. He has non had mucosal shed blooding as nosebleed or hematuria. MFA would sometimes necessitate hospital admittance for factor VIII transfusion. This is normally when he has hemorrhage or terrible hurting due to a haemarthroses or a hematoma. At other times he would have the transfusion at the day care and return place. His parents would convey him once more to the infirmary for the following dosage till the hurting and puffiness in the joint resolutenesss. If a transfusion were required at dark when the day care is non unfastened, MFA would travel to the pediatric ward where the medical officer would be able to administrate the factor VIII. His symptoms would better with the factor VIII transfusion. MFA is an active male child who likes playing and running about. However his instructors in school restrict his physical activity to non-contact athleticss such as badminton and running. He is besides discouraged from unsmooth drama with his classmates. He wears elastic guards around his cubituss and articulatio genuss to protect them from hurt. However the elastic guards do non assist much as he still develops haemarthroses at those articulations. MFA is presently casting his decidual dentition. As such he requires factor VIII transfusion screen prior to tooth extraction. MFA is under followup at the pediatric clinic of Batu Pahat. He has defaulted the followup as his parents feel that nil much was done during the visits. He merely presents to the day care when necessitating factor VIII transfusion. MFA has besides been referred for physical therapy after episodes of haemarthroses which limit motion in the articulations. He has attended a few Sessionss of physical therapy in order to forestall contracture at articulations which have haemarthroses. He does non hold regular assignments. MFA is a member of the haemophilia society. His parents on a regular basis attend meetings where negotiations are given to educate parents on caring for haemophiliac kids. The members besides relate their experiences and promote one another. MFA has a medic qui vive necklace which says that he has haemophilia A. However, he rarely wears the medic qui vive. Past medical history MFA has non had any other infirmary admittances other than those due to haemophilia. Family history MFA is the youngest of three siblings. His senior sister is twenty old ages old and is good. His senior brother is 15 old ages old and has a bone cyst. He has undergone eight surgeries to mend the bone cyst every bit good as due to complications such as refractures. The wheelchair which MFA used at place was bought for his brother ‘s usage. MFA ‘s parents are good. There is no household history of hemophilia on his maternal side even though she is a bearer. MFA ‘s female parent has 3 brothers but all of them are good and do non hold hemophilias. There is no history of shed blooding upsets in the household. Social history MFA ‘s parents are both instructors. However they have to lose traveling to work frequently due to MFA ‘s status which necessitates frequent visits to the infirmary. As such, MFA ‘s female parent has a particular agreement with her schoolmaster which allows her to learn from 11 to 4 autopsy. As such, she is free in the forenoon to convey MFA to the infirmary when he needs it. His parents besides provide good support for MFA in that they frequently attend haemophilia meetings to update themselves on agencies to outdo attention for their kid. Birth history MFA was born at term in Hospital Batu Pahat. He was delivered through an elected cesarean delivery subdivision due to a breech presentation. There were no prenatal abnormalcies detected during everyday prenatal medical examination. There were no perinatal or station natal complications. He was nursed with his female parent after birth and discharged uneventfully. Developmental history MFA is presently in primary three of a spiritual school. He is an above mean pupil who finishes in the top 10 of his category. His instructors have no ailments about his school assignment. Developmental mileposts prior to this were all achieved at the appropriate times. Dietary history MFA is on an grownup diet now. He eats balanced repasts which are normally prepared by his female parent. He was breastfed till the age of seven months. Weaning was with porridge at the age of five months. Immunization history MFA has been immunized harmonizing to the immunisation agenda. After he was diagnosed with hemophilia A, his immunisations were done at the pediatric clinic under factor VIII screen. His last immunisation was at seven old ages of age. Student Name: Tan Hai Liang ID NO: M0409146 Name OF SUPERVISOR: Dr Kyin ROTATION: Pediatricss3 ) Findings ON CLINICAL EXAMINATIONOn general scrutiny, MFA was friendly and communicative. He was sitting in a wheelchair with a patch around his left mortise joint. There were some ecchymosis seen at his weaponries and thighs. He looked good nourished. He was non in terrible hurting. Anthropometric measurings: Weight: 24kg ( 10th to 25th centile ) Height:130cm ( 25th to 50th centile ) His critical marks were normal: Pulsation: 82 beats per minute Respiratory rate: 18 breaths per minute Blood force per unit area: 108/72 Temperature: 37 grades Celsius Examination of the lower limbs: There were ecchymosis seen on both lower limbs at the thigh every bit good as at the shin and calf. The left mortise joint was swollen and there was a contusion seen on it. It was stamp on tactual exploration but there was no addition in temperature. There was reduced motion of the left mortise joint articulation due to trouble. The right mortise joint articulation every bit good as both the left and right articulatio genus articulations were normal. There were no contractures seen. Examination of the upper limbs: There was besides some contusions seen on both the upper limbs. The cubitus and wrist articulations were normal on both custodies. The scope of motion for all the articulations on both upper limbs were normal. Examination of the cardiovascular and respiratory systems every bit good as scrutiny of the venters was normal. Student Name: Tan Hai Liang ID NO: M0409146 Name OF SUPERVISOR: Dr Kyin ROTATION: Pediatricss4 ) PROVISIONAL AND DIFFERENTIAL DIAGNOSES WITH REASONINGProbationary diagnosing: Haemarthroses of the left mortise joint articulation — — Evidence for: MFA has been diagnosed with hemophilia since the age of eight months. The articulations are a common site of shed blooding for hemophiliac. In add-on, MFA has had anterior episodes of hurting and puffiness in the joint similar to this episode. The hurting reduced when he was given factor VIII transfusion which farther supports this diagnosing. He besides has multiple contusions on his weaponries and legs which indicate that he has a hemorrhage upset. Differential diagnosing: 1 ) Juvenile Rheumatoid Arthritis The pauciarticular type of juvenile rheumatoid arthritis nowadayss with hurting and puffiness in the big articulations such as articulatio genuss, mortise joints and carpuss. It may show as symmetrical arthralgia or may merely impact one articulation. Evidence against: Juvenile rheumatoid arthritis normally nowadayss during childhood while MFA has been holding episodes of joint hurting and puffiness since he was an baby at eight months of age. Juvenile arthritic arthritis is besides associated with forenoon stiffness which MFA does non hold. MFA besides has easy contusing which is non a characteristic of juvenile rheumatoid arthritis 2 ) Septic arthritis Patients with damaged articulations are predisposed to infected arthritis. As such, a haemophiliac patient who has repeated haemarthroses may hold damaged articulations which are susceptible to infection. Evidence against: Patients with infected arthritis normally have fever while MFA did non. They are besides more common in patients who are immunocompromised. On physical scrutiny, there was no increased heat in the joint which would be more declarative of infected arthritis. 3 ) Ankle ligament hurt A sudden turn of the mortise joint may do a wrenching of the soft tissue and ligaments around the mortise joint doing hurting and puffiness. Evidence against: Master of fine arts did non writhe his mortise joint while playing. He simply knocked it against a stone. As such the mechanism of hurt does non propose that the ligaments were strained. He was besides able to bear weight after hitting his mortise joint and the puffiness and hurting bit by bit developed. This is contrary to what is expected in a sprained mortise joint where there would be immediate puffiness and hurting around the mortise joint. Student Name: Tan Hai Liang ID NO: M0409146 Name OF SUPERVISOR: Dr Kyin ROTATION: Pediatricss5 ) IDENTIFY AND PRIORITISE THE PROBLEMS1. Swelling at the left mortise joint MFA has hurting and puffiness at the left mortise joint articulation. He was in moderate hurting which he rates as 6 out of 10 on the hurting mark. Analgesics such as acetylsalicylic acid and NSAIDS are non recommended for him as they cause shed blooding in hemophiliac. As such the best agencies for rapid alleviation of the hurting and the swelling would be Factor VIII transfusion. 2. Hazard of joint devastation MFA is presently eight old ages old and is an active male child who enjoys playing with his friends. As such he is prone to injury from even mild injury. He has developed haemarthroses on an norm of every 3 months. Perennial haemarthroses at the same articulation could do devastation of his articulations taking to osteoarthritis, restriction in motion and development of contractures. A hold in intervention could besides do harm to the joint. As such, prompt and equal factor VIII transfusion is indispensable for MFA. He should besides be referred to the physical therapy section when the hurting has subsided. Physiotherapy would assist in forestalling the development of joint contractures 3. Hazard of shed blooding Due to his active nature, MFA is besides at hazard of terrible hemorrhage if he injures himself. He was last admitted to the infirmary for one hebdomad due to shed blooding when he fell while playing. There was terrible hemorrhage from his oral cavity and gums when he hit his face on a tabular array. MFA is besides presently casting his decidual dentition. As such, he is at hazard of gum hemorrhage from the site of tooth extraction. The most unsafe hazard is that of an intracranial bleeding 4. Hazard of perennial factor transfusions MFA requires frequent factor transfusion. As the factor VIII used in Batu Pahat is derived from human plasma, there is a hazard that MFA may acquire Hepatitis B, Hepatitis C or HIV infections. In add-on, MFA has non been screened for any of these infections. As such it is necessary for MFA to be screened as recommended by the Malaysian protocol for the direction of hemophilia. 5. Consequence of unwellness on school assignment and day-to-day activity MFA misses school for about a hebdomad on an norm of one time every three months. This may impact his public presentation in school. In add-on there is an addition demand for him to acquire good academic consequences as he would necessitate to believe about a hereafter with a calling that does non necessitate heavy physical activity due to his status. Trouble faced by caretakers MFA ‘s male parent and female parent are both working and frequently are forced to lose work in order to take attention of MFA when he develops episodes of hemorrhage. Both the parents are instructors who have understanding schoolmasters who sympathize with them and give them much leeway in order to care for their kid. However the uninterrupted emphasis of taking attention of a inveterate sick kid demands to be addressed. Support groups such as the haemophillia society would be able to assist the parents by giving them entree to other parents who face similar troubles. These parents would be able to promote one another and portion tips on caring for haemophilliac kids Student Name: Tan Hai Liang ID NO: M0409146 Name OF SUPERVISOR: Dr Kyin ROTATION: Pediatricss6 ) Plan OF INVESTIGATION, JUSTIFICATIONS FOR THE SELECTION OF TESTS OR PROCEDURES, AND INTERPRETATION OF RESULTSProbes done at 8 months of age by the national blood bank: 1. Curdling profile Justification: MFA presented with peliosis at his limbs which indicates that might hold a hemorrhage upset. As such a curdling profile would be utile to see if the curdling tracts are affected. Consequences: APTT prolonged. More than 90 seconds Interpretation: The drawn-out APTT indicates that the intrinsic tract is affected and that one of the factors in the intrinsic tract may be deficient. 2. Serum factor VIII degree Justification: To determine which specific factor that is lacking doing the hemorrhage upset. Consequences: Factor VIII degree: 0.6 % ( No inhibitors detected ) Interpretation: MFA has severe haemophilia A due to his Factor VIII degree being less than 1 % . He will react to factor VIII transfusion as there are no inhibitors to factor VIII detected. No probes were done for this presentation at the day care. I would propose the undermentioned probes: 1 ) A field radiogram of the ankle articulation AP and sidelong position Justification: In order to govern out other causes of the joint hurting such as infected arthritis or break at the joint. Possible grounds why it was non done: The clinical presentation of the patient did non propose that he has infected arthritis as he did non hold a febrility and the articulation was non ruddy. As the clinical image was typically implicative of a haemarthroses given that he is a hemophiliac, it would be unjust to the patient to subject him to an ten beam as this would intend he would be exposed to radiation every three months. 2 ) Full blood count Justification: A full blood count would be utile to see if there is an increased white cell count which may bespeak an infection. Possible grounds why it was non done: MFA is clinically good with no symptoms of infection such as febrility. As such a full blood count may non be necessary as it would likely be normal. There is besides a hazard of shed blooding or hematoma from venepuncture. Student Name: Tan Hai Liang ID NO: M0409146 Name OF SUPERVISOR: Dr Kyin ROTATION: Pediatricss7 ) Working DIAGNOSIS AND PLAN OF MANAGEMENT ON ADMISSIONWorking diagnosing: Haemarthroses of the left mortise joint due to Haemophilia A My proposed program of direction: I ) Factor VIII transfusion with a mark serum factor degree of 30 % eight hourly till the puffiness and hurting resolutenesss two ) Elastic patch and ice battalion around the left mortise joint three ) To rest the mortise joint articulation by non-weight bearing boulder clay swelling and hurting reduces four ) To analyze patient for joint malformation or contractures prior to dispatch from day care V ) Refer the patient to physiotherapy for joint rehabilitation of the affected articulation. six ) To educate the parents on attention for their kid and protective steps to forestall hurt. Student Name: Tan Hai Liang ID NO: M0409146 Name OF SUPERVISOR: Dr Kyin ROTATION: Pediatricss8 ) Summary OF INPATIENT PROGRESS ( INCLUDING MAJOR EVENTS, CHANGE OF DIAGNOSIS OR MANAGEMENT AND OUTCOMES )MFA was given 200 IU of Factor VIII transfusion. He was so asked to return the following twenty-four hours to be reviewed by the medical officer in charge. Merely one transfusion was deficient for the puffiness and MFA had to digest much uncomfortableness and hurting throughout the dark. This is despite the Malayan Paediatrics protocol recommendation that factor VIII is given every 8 to 12 hours. The ground for this could be the prohibitory cost of the factor. The following twenty-four hours MFA was given another 200 IU of Factor VIII transfusion in the forenoon and once more in the eventide, 12 hours apart. He was given two more transfusions on the 3rd twenty-four hours. The transfusions were given at the day care in the forenoons and at the pediatric ward at dark by the medical officer who was on call. The hurting and swelling resolved on the 4th twenty-four hours post hurt. He was examined by the medical officer and was told to merely return to the day care if he had another episode of joint puffiness or open hemorrhage. Student Name: Tan Hai Liang ID NO: M0409146 Name OF SUPERVISOR: Dr Kyin ROTATION: Pediatricss9 ) DISCHARGE PLAN, COUNSELLING AND MOCK PRESCRIPTIONDischarge program: I ) MFA was asked to rest him left mortise joint and to partly bear weight till it was wholly pain free. two ) Referral to the physical therapist for joint rehabilitation to be done Guidance: I ) MFA was advised to avoid athleticss which involve physical contact as the even minimum injury may do a bleed. two ) MFA ‘s parents were told to convey him back to the day care if there were any longer episodes of shed blooding into the articulations or self-generated hemorrhage. They were given a eventuality program to travel straight to the pediatric ward and see the medical officer on call if any hemorrhage were to go on when the day care is closed. three ) MFA and his parents were besides educated on complications that they need to look out for such as intracranial bleeding. They were taught about the marks and symptoms that they should be wary of. four ) MFA was encouraged to travel for physical therapy which he had antecedently defaulted. He was told about the dangers of joint devastation due to recurrent haemarthroses and how physical therapy may help in forestalling contractures. Student Name: Tan Hai Liang ID NO: M0409146 Name OF SUPERVISOR: Dr Kyin ROTATION: Pediatricss10 ) REFERRAL LETTER ( MANDATORY )Dr Tan Hai Liang, Paediatric Department, Hospital Batu Pahat Physical therapist, Physiotherapy section, Hospital Batu Pahat 27 May 2009 Dear sir, Patient ‘s name: Mohammad Faiz Affizuddin Patient ‘s I/c figure: ( B ) 630902-01-6092 Problem: Haemarthroses of the left mortise joint articulation Thank you for seeing this nine twelvemonth old male child who was diagnosed with Haemophilia A for the past eight old ages. He has had recurrent episodes of shed blooding into the articulations. The articulations most normally affected are the articulatio genus articulations and elbow articulations. His current presentation is for a haemarthroses of the left mortise joint articulation. Physical scrutiny: Inflammation and puffiness of the left mortise joint articulation. Tenderness on tactual exploration. Reduced scope of motion both active and inactive. He has been given Factor VIII transfusion which has reduced the puffiness and hurting. Kindly reexamine the patient and execute joint rehabilitation for him. He has good household support and his household could besides be taught exercisings to forestall joint contractures that can be done at place in position of his recurrent shed blooding into the articulations. Thank you. Yours genuinely,______________( Dr Tan Hai Liang ) Student Name: Tan Hai Liang ID NO: M0409146 Name OF SUPERVISOR: Dr Kyin ROTATION: Pediatricss11 ) Learning ISSUES IN THE 8 IMU OUTCOMES1 ) Family and community issues in health careHow are parents affected by holding a hemophiliac kid? I had the chance to speak to MFA ‘s parents and inquire them about the challenges faced when caring for him. They related many of their experiences and confided that many alterations to the life style of the household were done in order to accommodate to populating with and caring for a hemophiliac. Both parents have had to lose work on a regular basis due to MFA ‘s frequent infirmary admittances. Family activities besides are limited to light physical activity with minimum hazard of hurt. Furthermore MFA ‘s female parent admitted to ab initio experiencing guilty as she was the bearer of the cistron that leads to his status. As such, I wondered if hemophilia had an impact on parent ‘s quality of life in visible radiation of the many accommodations that they had to do to their life style. A survey by Beeton et al [ 1 ] involved 12 parents of kids with hemophilias whose age ranged from 18 months to 16 old ages of age. The parents were interviewed and qualitatively assessed on their experiences in caring for a kid with hemophilia. It found that medical direction often focused on assisting the hemophiliac adjust to his or her status with small accent on the wider household web. The early old ages of the kid ‘s life after diagnosing were characterized by the parents missing experience and feeling uncertain. This is coupled with the frequent demand of factor transfusion and the associated trouble in venous entree in babies and immature kids. Quality of life at the early old ages post diagnosing was found to be hapless due to parents experiencing ‘out of control ‘ . Parents caring for a hemophiliac kid besides reported that the manner in which they engaged with the people around them had changed. There was a necessity in being more self-asserting in order to protect their kid. This was confirmed by MFA ‘s female parent who relates that she had statements with the infirmary manager and schoolmaster of MFA ‘s school in order to take a firm stand on particular steps to be put into topographic point to better MFA ‘s quality of life. The survey besides found that female parents normally took up a greater duty in caring for the kid. Fathers who were at work during the twenty-four hours did non hold the same degree of experience and this could be a beginning of struggle between parents. Parents were besides found to hold higher degrees of emphasis and anxiousness. However the degree of the emphasis and anxiousness was dependent upon on the phase that parents had achieved in pull offing the status every bit good as successful version. Another survey by Bullinger et al [ 2 ] showed that the quality of life for patients and households with hemophilia was higher when compared to patients with other chronic unwellnesss such as asthma. This shows that households with hemophiliac are able to populate a comparatively normal life with good quality of life if certain stairss were taken to accomplish successful version. The survey found that betterment in quality of life can be attained by supplying an environment in which patients and parents experience understood and good informed. In decision, I learned that hemophilia has a profound consequence, non merely on the kid who has the disease but besides on his primary caretakers which are his parents. As such I need to besides ask about how parents are get bying and offer professional aid such as reding if necessary.2 ) Critical thought and researchIs coagulating factor dressed ore prophylaxis effectual in the direction of patients with hemophilias?A paper by Ljung [ 3 ] proposed that direction of a patient with hemophilia should travel off from concentrating on the upset itself and alternatively look towards keeping a healthy kid. This means that patient ‘s should non be repeatedly managed with factor transfusions when they present with shed blooding but alternatively be kept healthy by forestalling the hemorrhage from go oning in the first topographic point. As such the writer proposed that primary contraceptive therapy should be the gilded criterion in the direction of patients with hemophilias. However is coagulating factor dressed ore prophylaxis effectual in pull offing patients with hemophilias, and what are the associated factors which prevent this direction from being a practical option? I looked at a Cochranre reappraisal by Stobart et Al [ 4 ] which analysed four separate surveies affecting 37 patients. The consequences of the reappraisal showed that there was a statistically important difference in the decrease of shed blooding episodes in patients who were given standard prophylaxis when compared to a placebo. It besides found that secondary results such as clip loss to school and employment due to the unwellness was statistically significantly reduced among those having primary prophylaxis compared to a placebo. The reappraisal besides quoted one survey which showed that a twice hebdomadal extract of higher dosage of factor dressed ore had a statistically important advantage in cut downing the figure of bleeds a twelvemonth when compared to a lower dosage and less frequent disposal of transfusion. However the writers concluded that there was deficient grounds from randomized control tests to urge the usage of primary contraceptive factor extract in the direction of patients with hemophilias. An independent retrospective survey by Khoriaty [ 5 ] showed that primary prophylaxis has some promise. The survey recruited 133 patients with Haemophilia A and B with a average age of 27.93. It compared the 91 patients who were on primary prophylaxis and the staying 42 patients having on-demand intervention when they developed shed blooding. The survey found that there was a statistically important decrease in the figure of self-generated shed blooding per twelvemonth. Patients on primary prophylaxis were found to hold 3.2 bleeds per twelvemonth while those who received on-demand therapy bled 5.7 times per twelvemonth. It found no statistical difference between the two groups in footings of hemorrhage after injury. However the consequences for this survey needs to be read with attention due to the big age scope. Further surveies need to be done for the pediatric age group due to differences such as a higher leaning for injury and hurt in active kids compared to grownups who are better at caring for themselves. One ground why primary prophylaxis is non used in the intervention of haemophiliacs despite its promise is the high cost of the factor VIII. One phial of 200 IU costs in the part of RM 800. As such it may non be cost effectual for primary prophylaxis to be carried out particularly in the context of the Malaysian health care system with its limited budget. A cost effectivity analysis by Miners et al [ 6 ] in England showed that it would be & amp ; lb ; 547 to forestall one episode of shed blooding from go oning. This cost is mostly prohibitory in the Malayan context. In decision I found that there is grounds that primary prophylaxis has much promise in the bar of shed blooding among haemophilia patients but extra surveies need to be carried out particularly in the local environment in order to determine the cost-effectiveness of primary prophylaxis.3 ) Self directed life long larningWhat is the hereafter in footings of direction of hemophilia? The direction of hemophilia is presently with factor transfusions which aim to halt hemorrhage when it has already happened. The other option is primary prophylaxis with regular factor extracts to forestall hemorrhage. However this attack is dearly-won and does non cover with the job of patients developing inhibitors which make transfusions uneffective. As such, research workers are looking into a agency for a remedy of hemophilia. This remedy is by utilizing cistron therapy. The aim of cistron therapy is to redact a faulty cistron sequence to accomplish complete reversion of disease phenotype in the life-time of the patient. Haemophilia is seen as the ideal campaigner for cistron transportation therapy as foremost there are many cell types which are able to synthesise biologically active coagulating factor. Second, there is a broad remedy window which makes it unneeded to hold rigorous cistron look. Third there are big and little animate being theoretical accounts that permit the survey of safety and efficaciousness prior to induction of human tests. [ 7 ] Phase 1 clinical tests are presently being done utilizing largely viral vectors to infix the cistron. Retroviruss have shown promise in this therapy. The cistrons are inserted via developing hepatocytes or hematopoietic root cells. Presently safe long term look of coagulating factors has been successfully achieved in big carnal theoretical accounts of hemophilias utilizing multiple cistron transportations. [ 8 ] Gene transportation therapy nevertheless still faces many obstructions before it can be seen as a feasible therapy for hemophilia. There is hazard of experimentation in worlds in order to formalize this therapy. Many inquiries besides remain unreciprocated such as inhibitor development after the interpolation of the cistron and besides the transmittal of the extra cistron to the kids of the patient who receives the cistron therapy. One paper suggested a generous timeline of at least 20 to 30 old ages before the potency of cistron therapy can even be considered. These issues are ‘merely medical ‘ issues. Religious and ethical issues besides have to be taken into consideration before prosecuting this direction. In decision, I learned that though there is much potency in this field of cistron therapy, much research still has to be undertaken to determine its safety every bit good as efficaciousness. However it has been a valuable experience in larning about new modes of intervention and to catch a glance of what the hereafter holds. This has taught me to go on larning as there are ever new sentiments and therapies available in the direction of any unwellness. 4 ) Professionalism, moralss and personal development What are the ethical deductions of familial proving for haemophilia? After MFA was diagnosed with haemophilia, his immediate household underwent familial testing. The proving revealed that his female parent was a bearer and that his senior brother and senior sister were normal. The familial testing was done voluntarily. There is no recommendation in the Malayan Paediatric protocol for familial testing to be done. Familial testing is normally done in patients with no clear household history in order to determine which parent is a bearer so that farther stairss of direction can be carried out. These farther stairss may include offering familial testing to the siblings of the bearer parent and besides reding about hazard of holding extra kids. However familial testing besides raises many ethical inquiries. First there is guilt, heartache and ego incrimination when a female parent with no known household history of hemophilia discoveries that she was the cistron bearer that passed it on to her kid. A paper by Thomas et al [ 9 ] on attitudes towards familial proving in an Australian community found that female parents who were ‘sporadic ‘ bearers ( no known household history of hemophilia ) were had feelings of guilt. Performing familial testing to determine that a female parent of a haemophiliac kid is a bearer would merely be of value if extra stairss were taken such as offering familial testing to the female parent ‘s siblings. This in itself would raise inquiries of confidentiality and revelation since offering the testing would necessitate the physician to unwrap to the other household members that the female parent is a bearer. This revelation could so take to stigmatisation. In this specific instance, MFA ‘s female parent was found to be a bearer. She related that she felt anguished at ‘causing ‘ her boy to endure much hurting. The cognition that the female parent was the bearer who had passed on the cistron to her boy did non change the direction of MFA. As such there was small virtue in executing the familial testing in this instance. A 2nd consideration of familial testing is the deductions that it has on a individual ‘s determination of whether or non to hold kids. This is once more more relevant for female bearers. Carriers should be counseled that there is a 50 per centum opportunity that their kid would hold hemophilias if he were a male child. However the ethical issue arises when there is no agency of correlating between the genotype and phenotype. [ 10 ] Just because the kid may hold hemophilia does non foretell the grade of badness of the hemophilia. The lone means to cognize for certain about the position of a foetus in footings of whether he would hold hemophilias and the grade of badness is by making antenatal familial proving such as chorionic villi sampling. Prenatal familial proving itself is associated with many ethical issues such as the deductions of transporting out such a trial. Would the foetus be terminated? There is legal leeway for expiration if it can be proven that the kid ‘s unwellness would convey about mental hurt to the female parent. Where do we pull the line to make up one's mind that such a foetus has excessively terrible a haemophilia so as to justify expiration? Who makes the determination? In the instance of MFA, the parents decided non to hold any more kids due to the hazard of holding another hemophiliac kid. It ca be seen that the familial testing had a profound impact on their determination. However proper and thorough familial guidance was non given to the parents. In decision I learned that familial proving for hemophilia is fraught with many ethical considerations. It should merely be offered when proper followup such as guidance, support and options can be offered to those undergoing the trial. In the absence of proper model of support, it may be better to keep back familial testing.

Metaphorical Criticism of American Beauty Essay

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American History Since 1877 Essay Example | Topics and Well Written Essays - 750 words

American History Since 1877 - Essay Example However, challenges still loomed for blacks in the 1870s such as the â€Å"Ku Klux period†1. However, since the 1870s, America has undergone numerous changes to become the modern day world’s super power. This paper examines American history since 1877 to the present date. After the civil war, most of the population in America moved to the west and towards the end of the 19th century, cities begun to expand. During this period, America also witnessed growth contributed by industrial revolution thus opening up more businesses and creating the principle of laissez faire.Further, employment opportunities where created during this period and marked the introduction of wage workers. Regulations such as protective tariff were also introduced on traded commodities and to favor domestic business owners. On the other hand, the whites gained control of the South during this period and denied blacks voting rights. The barring of blacks from voting was made possible by the introduction of new laws and intimidation. Further, the relationship between the Federal government and Native America also suffered during this period where most of the Natives were forced into reservations2. In the early decades of the 20th century, saw the rejection of the principle of the laissez-faire economy emphasized in the Gilded Age. Leaders in America during this era were more progressive in terms of pressing for new changes. An example in this sense, involves pressurizing the government to regulate corporations. Consequently, the Federal government endeavored in breaking up large monopolies in the country. Progressive reformation during this period also saw the introduction of tax on the rich as a means of redistributing wealth to the disadvantaged in the society. This period further marked the transition from a republican federation of states to democracy of national citizens. However,

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PHI201 MOD 3 SLP - Essay Example Out of these circumstances, I have observed that senses are often put to doubt when tested by personal encounters of various stimuli to respond to. On one occasion, I was about to cross the street where pedestrians have become accustomed to the defective traffic lights. Like them, I would rather trust my instincts and be sensitive to the natural sound an approaching automobile creates. That scheme has typically worked until one broad daylight when a passing truck was caught by my peripheral vision, I felt all along that the vehicle was significantly far from view that I did not at all hesitate to start making the first step across the lane. Then the next thing I knew – shock paralyzed my entire body and held me from where I stood having realized that the truck in great speed just swished by when I was barely an inch from the point of contact, the moment of sure dread. Owing to my lousy attitude that day, I was thankful that God and my sluggish pace spared me from the life thief where no doubt I would have been hit had I stridden or quicken forward with less than half my second step. It was so hard to believe I kept on as king and exclaiming to myself ‘How could that be?!’ The manner by which I perceived the incident told me nothing more than to be confident about the coming of truck from a distant spot. Hence, while I still count on my senses, such near-death experience has since changed the way I treat perceptual efforts in relation to physical and emotional security. Others testify to a case in which they tell of seeing yet eventually admit that they merely have mistaken what is seen for something else already at the back of their heads. Perceiving an object by means of projecting it from a recurring image in mind readily deceives one who has learned to be perceptive and establish dependence on common occurrences from which the person may associate someone or something to another

Blindness Essay Example | Topics and Well Written Essays - 1000 words

Blindness - Essay Example Some of the causes include infections, injuries, lack of glasses, trauma, etc. Blind students are also taught using various technologies, including Braille and assistive computer technology. These technologies enable students to read and listen to lecture notes, presentations, course materials and other reading materials. Causes of blindness depend on the socioeconomic conditions to which a person is exposed. They include causes that affect the eye directly and those that affect visual processing centres like the brain. In developed economies, the primary causes of blindness include macular degeneration, traumatic injuries and ocular diabetes complications. In developing and underdeveloped nations blindness is caused primarily by infections, glaucoma, lack of glasses, injury, and cataracts. Some of the infections that lead to blindness in underdeveloped countries include onchocerciasis (river blindness), leprosy and trachoma. The herpes simplex is the most common cause of blindness in developed countries. There are also other causes of blindness such as retinopathy, deficiency of vitamin A, diseases affective the retina or optic nerve e.g. stroke, inflammation, eye malignancies, abnormalities of the congenital, hereditary eye diseases, and chemical poisoning. According to Bourne et al (2013), catarac ts and macular degeneration are the leading causes of blindness. Cataracts affect people from developing and underdeveloped world while macular degeneration mainly affects people from developed countries. Blindness can also be caused by amblyopia, or the lazy eye. This refers to the condition in which a child is born with poorer vision in one eye than the other (NIH Medline Plus, 2015). Untreated amblyopia leads to vision loss and blindness. As the child grows, the brain ignores images from the affected eye, leading to loss of vision in that eye as the child enters teenage stage of life. The condition starts when one of the child’s eyes develops a

Health Economics of Medicine Essay Example | Topics and Well Written Essays - 2000 words

Health Economics of Medicine - Essay Example The value of Health Economics is indispensable in a society. Its scarcity is a primary concern especially among countries without ample resources to provide healthcare (Culyer, 1989). Another major issue that makes Health Economics important is the mode of distribution. There have been situations showing lack of logistic strategies that effectively deliver health to major recipients. Finally, the sustenance of supply and allocation of health care makes Health Economics valuable. In ensuring both the necessities are satisfied, costs have to be incurred consistently. It is the spending capacity of countries that decide supply and distribution of healthcare. According to Fuchs (1996, pp.1-24), the level of expenditures incurred by governments in healthcare delivery has increased precipitously. The sudden rise in cost can be attributed to intellectual advances, greater availability of information, and the ever-increasing demand for such service. The dedication of government spending to health care services results to various economic sacrifices. Aside from health, there are pressing needs that the society needs to acquire. Concentration in healthcare looms problems such as forging quality education and the generation of sustainable income through investments and government spending. Direct costs of delivering healthcare involve purchase of medicines, establishments of medical institutions, and hiring of personnel knowledgeable of health services. Other costs also include research and development, which at present is the most critical item being propagated by governments. Moreover, the government needs to incur indirect costs such as building of infrastructures to ensure that transportation and communication improves healthcare delivery. Furthermore, the marginal cost of health care needs to be evaluated. Unlike the total cost, which is simply an aggregate, marginal cost

IT Project problems Essay Example | Topics and Well Written Essays - 500 words

IT Project problems - Essay Example The project was a good example of organizational problems leading to failures in IT projects. The key stakeholders were Deloitte and the state. Deloitte was to blame for the mishap due imminent organizational issues as will be discussed. There was lack of clear communication of what would be termed as the deliverable. In such a case, it was possible to deem the project as a success without much questioning. Krigman (2013) states that the Deloitte group simply understated the problems as â€Å"issues and challenges† and that the systems were in a working condition in other states. This was a technical lapse owing to the fact that the project at hand was actually cancelled, after the long time and expenses. Success in an IT project depends on a number of factors, which lie under the realm of the management. Amongst these are time, budget, value, quality, professionalism and satisfaction to the stakeholders. It is upon the project manager to ensure that these factors are met in order to deem a certain project as successful. In view of the case project, none of this was meant, meaning that the project was a critical failure. As part of the ten factor model of project implementation, management support is a crucial agent in distinguishing success from failure in projects. Project management is deemed to depend on the management for authority and direction and also as a channel for implementation of the goals and plans of the organization. The manner in which the management supports a project determines the degree to which the clients will accept e same project. Thus, top management support is a combination of the resources allocated for the project, as well as the support available when a crisis occurs. In order to successfully implement projects, the management should be strict in standard guidelines of the project lifecycle. After the concept is adopted, proper planning should ensure that all necessary requirements are put in place.

A Doll’s House Essay Example for Free

A Doll’s House Essay In his book A Doll’s House, Ibsen explores the ideological struggle of gender roles in a marriage where the wife Nora must maintain a helpless role and the husband Torvald must appear as the sole familial support. Henrik Ibsen has been able to drive this point home very powerfully in A Dolls House. Nora and Torvald, the main characters, belong to an ordinary middle-class family and the stereotypes in gender roles are very obvious and are most prevalent in this milieu. The coming of age of Nora and of women in the fin-de-siecle brought the issue of gender roles in society and the emancipation of women to the fore. The so called tragedy that befalls Torvald is of a private nature but its enactment has implications for the whole society. â€Å"In closing her door on her husband and children, Nora opened the way to the turn-of-the-century women’s† (Finney: 91). The play brings out the hypocrisy behind Torvald’s obsession with keeping up appearances and encouraging Nora to behave in a childish, helpless way to make him feel important and assert his masculine strength. Nora laments the fact that she had remained a doll-child and a doll-wife all her life. She had passively accepted this role to conform to the norms of society. She knew that she was expected to play the role of a pretty â€Å"featherbrained† woman who needed to be petted and taken care of constantly. She realized that neither her father nor her husband had given her enough credit to be a responsible and mature human being and be taken seriously. She knew that the oft repeated plea â€Å"But I cant get on a bit without you to help me† (Dolls House, II) was in effect a result of her utter dependence on her husband; a dependence which was encouraged by Torvald and the society at large. Torvald was protective and caring of Nora but what he actually was trying to achieve was have complete control over her thoughts and actions. He was the mainstay of the family and Nora was the limpet hanging on to his masculine strength and making herself agreeable to him in order to remain in his favor. At the end of the play, the misfortune is more about Torvalds failure to maintain the illusion of his being the most upright, principled and in short, the most perfect man. His realization that he had fallen in the eyes of a woman whom he felt condescendingly about heightens the sense of tragedy. He would often preach to Nora about her lack of principles which she had apparently inherited from her father and reprimanded her by calling her â€Å"a hypocrite, a liar—worse, worsea criminal! The unutterable ugliness of it all! For shame! For shame! †(A Dolls House: III). The unmasking of his own hypocrisy and the ugliness of being exposed to be a petty, judgmental and selfish man makes the audience understand that in spite of all his sermonizing, he was the one who lacked any principles as he was ready to drop everything and forget about the whole incident as soon as his own back was covered. In the final analysis of the ideological struggle depicted in this play, Nora, who was actually happy in enacting her gender stereotype during the beginning of the play and was elevated to a much higher position due to her realization of her identity and the consequent struggle to assert her independence. Nora’s recognition of her transformation from being â€Å"simply your little songbird† to a whole human being with potential to grow to be a woman of more substance is the first step towards her trying to resolve the conflict within her. She also understood that Torvald had always maintained a certain facade with her, which was contrary to his actual being. She says, â€Å"I realized that for eight years Id been living here with a strange man † (Doll House: III) and that steeled her determination to begin from scratch and live up to her potential. At the end of the play Nora appears to be strong and determined to the point of being heartless as she abandons her home, husband and children in quest of her true identity and knowledge of the ways of the world. The topic of feminism in this play deals with double standards and marriage (Finney: 92) A blatant example of this is Torvald’s condemnation of Nora as a â€Å"hypocrite and liar† when in reality it is Torvald who is the biggest hypocrite. His tall words about honor and honesty are shallow and he exposes himself as the small, petty person he is in spite of trying to assert himself in the stereotypical masculine role that society assigned to the male gender. Even the minor women characters in the play that of Mrs. Linde and Anne, the maid, demonstrate strength and fixity of purpose that the male characters Torvald, Dr. Rank and Krogstad fail to display. Ibsen was sensitive to feminine issues and though he himself proclaimed himself a ‘humanist’ rather than a ‘feminist’ his insight into the feminine psyche and his portrayal of women is evident in his memorable plays. He is able to make it clear to the audience that Nora’s helplessness and dependence on Torvald was put on. It became more obvious when we come to know that Nora had actually forged her father’s signature in order to take a loan to get Torvald to Italy in order to save his life. That she was capable of taking such drastic decisions and has the courage to work at copying and repay the loan to Krogstad without Torvald’s knowledge is a clear indicator that left to her own devises she was quite decisive and better at managing crisis than Torvald. In conclusion, it is indeed true that Nora Helmer tried her best to enact the gender role assigned to her by the society. However, when ideological differences arose she struggled to cast off the garb of the helpless little lady and emerged a stronger and more mature person. In the play a clear happy ending was not evident and the audience was left to interpret Torvalds hope for a â€Å"most wonderful thing† as a silver lining to an otherwise grim close to the play.

Creating Safe Environments Essay Example for Free

Creating Safe Environments Essay Collaboration with parents is one of the most challenging and critical issues that cause misunderstandings within the classroom and throughout the school building. It is a non-negotiable expectation among parents and teachers that include building a network between and among parents and teachers. It involves a sense of mutual respect as well as an understanding of different viewpoints. Teachers should be mindful that building relationships early in the school year will result in a positive classroom environment in which students have a secure place to learn. Parents and teachers should share expertise regarding the student in which information about learning styles are presented in a non-threatening manner. Teachers should be able to use limited amounts of teacher language so parents are able to understand expectations within the classroom as well as establish guidelines for following up on strategies at home. As a parent, I would appreciate a relationship with the person who spends most of the day with my child. I would gain insight into the way my child thinks in various situations to create a deeper understanding of relationships in the real world. The need for character education for parents lies in the fact that children should be shown examples of good character both at home and at school. â€Å"School has to build the work that the family does† (Lickona, 2009). Parents should unequivocally be involved and taught character education strategies. Much of what we see as teachers is a reflection of a poor home environment as parents who live complicated lives. Many are single parents and lack the time or resources to handle the complex problems of children today. They want nothing more than for their children to be successful, but as educators, it is our responsibility to provide resources for parents such as strategies and techniques, parenting courses with childcare and methods which foster values that all people should acquire in society. In this ever changing world, I, as a parent would welcome some insight to how my children are becoming part of the world they live in. This collaboration in character education should be purposeful as is our teaching. The purpose of character education should change the way the classroom works and feels, not just the way each member acts (Lichona, 1991).

Crude Drugs: Pharmacognostic Investigation

Crude Drugs: Pharmacognostic Investigation Introduction Microscopical examination and pharmacognostic evaluation of phyto drug may not apparently bear any direct co-relation with pharmacological and phytochemical evaluations. One should always remember that botanical identity of the phyto drug is an essential pre-requisite for undertaking the analysis of medicinal properties of any plant. If botanical identity of drug happens to be doubtful the entire phytochemical and pharmacological work on the plant becomes invalid. Thus the botanical identity of a crude drug threshold in the process of pharmacological investigations. Pharmacognostic Evaluation A systematic pharmacognostic study was carried out on the herbal drugs selected, to describe them more scientifically and to identify specific characteristics, if any, which will be helpful in the quality assurance and standardization of these plant drugs. Leaf Constants Determination of Stomatal Index Stomatal index is the percentage which the number of stomata form to the total number of epidermal cells, each stoma being counted as one cell. Stomatal index was be calculated by using the following equation. I = S X 100 E+S I=Stomatal index, S=No. of stomata per unit area, E=No. of epidermal cells in the same unit area. Middle part of the leaf was cleared by boiling with chloral hydrate solution. The lower epidermis was peeled by means of forceps and mounted on the slide with glycerine water. Camera lucida and drawing board were arranged for making drawings to scale. A square of 1mm was drawn by means of stage micrometer. The slide with cleared leaf (epidermis) was placed on the stage. The epidermal cells and stomata were traced out. The number of stomata present in 1sq mm area was counted. (Stomatal Number). The result for each of the ten fields was recorded and the average number of stomata per sq.mm was calculated. The stomatal index was determined using the above formula. The slides were prepared for Gynandropsis gynandra,(fig.2). The Stomatal number and Stomatal index values are given in Table.2. Determination of Vein-Islet Number Vein-islet is the small area of green tissue surrounded by the veinlets. The vein-islet number is the average number of vein-islet per square millimeter of a leaf surface. It is determined by counting the number of vein-islets in an area of 4 sq.mm of the central part of the leaf between the midrib and the margin. A portion of leaf was cleaned by boiling in chloral hydrate solution for about thirty minutes and slide was prepared. Camera lucida and drawing board were arranged for making drawings to scale. Stage micrometer was arranged on the microscope and using 16 mm objective, a line was drawn equivalent to 1 mm as seen through the microscope. A square was constructed on this line. The patter was moved so that the square is seen in the eye piece, in the centre of the field. The slide with the cleared leaf epidermis was placed on the stage. The veins which are included within the square were traced off, completing the outlines of those islets which overlap adjacent sides of the square. The number of vein islets in 1sq mm was counted. (The slides were prepared for Gynandropsis gynandra,(fig.5)). The average number of vein islets in the four adjoining squares gave. The Vein islet number.(Table -3) Determination of Palisade Ratio Palisade ratio is the average number of palisade cells beneath one epidermal cell of a leaf. It is determined by counting the palisade cells beneath four continuous epidermal cells. A piece of the leaf was cleared by boiling in chloral hydrate solution for about thirty minutes and slide was prepared. Camera lucida and drawing board were arranged for making drawings to scale. Using 4mm objective, the outlines of four cells of the epidermis were traced off. The palisade layer was focussed and sufficient cells were traced off to cover the tracings of the epidermal cells. The outlines of those palisade cells which are intersected by the epidermal walls, were completed. The palisade cells under the four epidermal cells were counted. The average number of cells beneath a single epidermal cell was calculated. (The slides were prepared for Gynandropsis gynandra,(fig.8). The determination was repeated for five groups of four epidermal cells from different parts of the leaf. The average of the results gave the palisade ratio. (Table-4) Histology of Gynandropsis gynandra: Midrib of Leaf: The transverse section of midrib of Gynandropsis gynandra Linn comprises of the epidermis, cortex, endodermis and vascular bundles. (fig.13) Upper epidermis: Comprises of barrel shaped cells which are closely packed, devoid of chloroplast and possess glandular trichomes. Cortex: Below the epidermis layers of cortical cells are present which are made up of polygonal parenchymatous cells. Endodermis: Endodermis is made up of rectangular barrel shaped cells with casparian thickenings. Pericycle: Below the endodermis three layered pericycle is present which is made up of parenchymatous cells. Vascular Bundles: A four to five layered phloem tissue is present that is made up of thinwalled phloem parenchymatous cells and phloem companion cells. Xylem tissue is made up of xylem elements, xylem parenchyma and xylem companion cells. Lower Epidermis: Is made up of polygonal cells which are closely packed together. 2.4.2 Stem: Transverse section of Gynandropsis gynandra Linn stem comprises of epidermis, exodermis, cortex, endodermis and vascular bundles. (fig.14) Epidermis: External layer with tightly joined cells that are devoid of stomata. This layer is usually termed as rhizodermis. It is also known as epiblema. This layer with covering trichomes dries and its place is taken by typical secondary boundary tissue called exodermis having glandular trichomes. Exodermis: This layer is present below the epidermis and is often regarded as a protective layer. The walls of the cells become suberized. Eames, in 1947, regarded this as hypodermis; Foster and Guttenberg, in 1943, gave it the name exodermis because of the presence of suberin in its walls. The suberin lamella develop on the inner side of the primary wall. They differ from cork cells since they contain protoplasmic contents. Cortex: The cortex is comparatively simple in histology and is generally composed of thin walled cells with lots of intercellular spaces. The cells are arranged in concentric layers with cells in each layer alternating with others. Endodermis: It is a distinct layer of cells differentiated from the innermost layer of cortex. The layer is uniseriate, made up of barrel shaped cells. Casparian strips are present radially. Pericycle: Below the endodermis, a few layers of parenchymatous cells are present which make up the pericycle. Vascular Bundles: The stem exhibits secondary growth, hence a complete ring of cambium is formed. A distinct secondary phloem is visible on the outer side. There is outer fascicular cambium which is made of parenchymatous cells. The phloem consists of phloem fibres, sieve tubes and companion cells. The secondary xylem shows distinct vessels and forms a continuous band interrupted here and there by narrow rays which are uniseriate. The secondary xylem constitutes a large portion of the bundles; it is present on the inner side and consists of vessels with simple perforated tracheids with a few simple pits on radial walls and some xylem parenchyma. Pith: Thin walled or thick walled cells filled with tannin and crystals of gypsum constitute the small pith. Stomata: Anisocytic or cruciferous (unequal) type of stomata which occurs in Capparadaceae family. The stoma is usually surrounded by three or four subsidiary cells, one of which is markedly smaller than the others. (fig.15) Physico Chemical Evaluation of Crude Drugs Extractive Values Extractive values are useful for evaluation of crude drugs and give an idea about the nature of chemical constituents present in them. The amount of extractive a drug yields to a given solvent is often an approximate measure of a certain constituent or group of related constituents the drug contains. In some cases the amount of a certain constituent or group of related constituents the drug contains, in some cases the amount of drug soluble in a given solvent is an index of its purity. The solvent used for extraction should be in a position to dissolve quantities of substances desired. Determination of Alcohol Soluble Extractive 5 g of macerated and air-dried coarse powder of drug was mixed with 100 ml of 95% alcohol in a closed flask and kept for 24 hours, shaking frequently during the first 6 hours and then allowed to stand for 18 hours. Thereafter, it was filtered rapidly taking precautions against loss of the solvent. About 25 ml of the filtrate was evaporated to dryness in a tared, flat-bottomed shallow dish, dried at 105o C and weighed. The percentage of alcohol-soluble extractive was calculated with reference to the air-dried drug. Determination of Water Soluble Extractive Proceeded as directed for the determination of alcohol soluble extractive, using chloroform water I.P. as a solvent. Determination of Chloroform Soluble Extractive Proceeded as directed for the determination of alcohol soluble extractive, using chloroform as solvent. Determination of Petroleum Ether Soluble Extractive Proceeded as directed for the determination of alcohol soluble extractive, using petroleum ether as a solvent. (Table 6) Loss On Drying About 5 g of powder was accurately weighed, placed in a petri-dish and dried in hot-air oven at 110Â ° C for four hours. After cooling, it was placed in a desiccator. The loss in weight was recorded. This was repeated till constant weight was obtained and % Loss on Drying was calculated with reference to the air-dried drug. (Table 7) Determination of Ash Values Ash values are helpful in determining the quality and purity of crude drugs in powdered form. Ashing involves an oxidation of the components of the product. The total ash usually consists of inorganic radicals like carbonates, phosphates, silicates and silica of sodium, potassium, magnesium and calcium. A high ash value is indicative of contamination, substitution or adulteration. Sometimes, inorganic variables like calcium oxalate, silica, carbonate content of crude drug affects total ash values; such variables are then removed by treating with acid (as they are soluble in hydrochloric acid) and then acid-insoluble ash value is determined. Ash insoluble in hydrochloric acid is the residue obtained after extracting the total ash with hydrochloric acid. This acid-insoluble ash value particularly indicates contamination with silicious materials like earth or sand. Water-soluble ash is that part of the total ash content which is soluble in water. It is a good indicator of either previous extraction of water soluble salts in the drug or incorrect preparation. For the determination of various ash values viz. total ash, acid-insoluble ash, water-soluble ash, the shade dried parts of the selected plant materials were powdered and passed through sieve no:40 and studies were carried out. The values vary within fairly wide limits and is therefore an important parameter for the purpose of evaluation of crude drugs. Determination of Total Ash A flat, thin porcelain crucible was weighed and ignited. About 2 g of the powdered drug was taken into the crucible. The crucible was incinerated at temperatures not exceeding 4500C, until free from carbon.The crucible was cooled in a desiccator and weighed. The procedure was repeated to get constant weight.The percentage of total ash was calculated with reference to the air dried drug. (Table No.8) Determination of Acid-insoluble Ash The total ash obtained was boiled with 25 ml of 2 M hydrochloric acid for 5mins. The insoluble ash was collected on an ashless filter paper and washed with hot water. The insoluble ash was transferred to a pre-weighed silica crucible, ignited, cooled, weighed and procedure was repeated to get constant weight. The percentage of Acid-insoluble ash of the crude drug was calculated with reference to the air-dried sample of the crude drug. (Table No.9) Determination of Water-soluble Ash The total ash obtained was boiled in 25 ml chloroform water for five minutes. The insoluble ash was collected on an ashless filter paper and washed with hot water. The insoluble ash was transferred into pre-weighed silica crucible, ignited for 15 minutes at a temperature not exceeding 450o C. The crucible was cooled, weighed and the procedure was repeated to get constant weight .Weight of the insoluble matter was subtracted from the weight of the total ash. The difference of weight was considered as the water-soluble ash. The percentage of water-soluble ash was determined with reference to the air-dried drug. (Table No.10) Fluorescence analysis of the crude drugs: Many crude drugs show fluorescence when the sample is exposed to ultraviolet radiation. Evaluation of crude drugs based on fluorescence in daylight is not much used, as it is usually unreliable due to the weakness of the fluorescence effect. Fluorescence lamps (366 nm) are fitted with suitable filters, which eliminates visible radiation from the lamp and transmits ultraviolet radiation of definite wavelength. Several crude drugs show characteristic fluorescence useful for their evaluation. (Table No.11) Total Solid Content About 5 g of extract was accurately weighed in a petri-dish and kept in a hot-air oven and maintained at 110Â °C for four hours. After cooling, the loss in weight was recorded. This procedure was repeated till constant weight was obtained. (Table No. 12) Total solid content (%) = Loss in weight x 100/W W = Weight of the extract in grams Extraction Maceration The powdered materials were extracted with alcohol (95%) by cold maceration method. Weighed quantity of powdered crude drugs were taken into round bottom flasks with alcohol, in the drug to solvent ratio 1:3 and kept for maceration for a period of 7 days. Finally the flask was left undisturbed for 12 hrs and then the contents were shaker and filtered through Whatman filter paper No.1. The marc was re-extracted with drug solvent ratio of 1:2. The extracts were combined and concentrated in a rotary flash evaporator, till free from solvent. The extracts, thus obtained were stored in a refrigerator at 40C until used. (Table No.13) Qualitative Phytochemical Screening A spectrum of natural compounds like alkaloids, glycosides, tannis, essential oils and other similar secondary metabolites which exert physiological activity are synthesized in the plant, in addition to the carbohydrates, proteins and lipids utilized by man as food articles. A systematic and complete study of crude drugs should include a thorough investigation of both primary and secondary metabolites derived as a result of plant metabolism. The different qualitative chemical tests are to be performed for establishing profile of a given extract/fraction for its nature of chemical composition. The following tests were carried out on the extracts to detect various phytoconstituents present in them. Detection of Alkaloids About 50 mg of solvent free extract was stirred with little quantity of dilute hydrochloric acid and filtered. The filtrate was tested carefully with various alkaloid tests viz., Mayers Test, Wagners Test, Hagers Test, Dragendroffs Test Detection of Carbohydrates About 100mg of the extract was dissolved in 5 ml of distilled water and filtered. The presence of carbohydrates were tested by Molischs Test, Fehlings Test, Barfoeds Test and Benedicts Test Detection of Glycosides For detection of glycosides, about 50 mg of extract was hydrolyzed with concentrated hydrochloric acid for 2 hrs on a water bath, filtered and the hydrolysate was subjected to the Glycoside testa viz., Borntragers Test, Legals Test, Detection of Saponins Foam or Froth Test Detection of Proteins and Amino Acids About 100 mg of extract was dissolved in 10 ml of distilled water and filtered through Whatmann No.1 filter paper and the filtrate was subjected to tests for proteins and amino acids. Viz., Millons Test, Biuret Test, Ninhydrin Test Detection of Phytosterols and triterpenoids: Tested by Libermann Burchards and Salkwoski test Detection of Phenolic Compounds and Tannins Tested by Ferric chloride test, Gelatin test, Lead acetate test, Alkaline reagents, and Shinoda test or Magnesium Hydrochloric acid reduction Thin Layer Chromatography Thin Layer Chromatography of extracts was done by using standard procedures and is mainly used for the detection of the nature of phytoconstituents present. Thin Layer Chromatography is a very effective technique for the separation of chemical constituents of an extract and for their identification. The history of TLC has been reviewed by various authors. A major breakthrough in this field was the commercial availability of convenient precoated plates in the early 70s Pharmacopoeias are increasingly employing this technique for assessing the quality and purity of compounds of both synthetic and natural origin. TLC profiles developed for an extract from a define solvent system and other parameters could be used as a fingerprint in comparative qualitative evaluation of herbal drugs. The trend of evaluation by this method is becoming popular in view of its simplicity and reproducibility. TLC is an important analytical tool in the separation, identification and estimation of different classes of natural products. In this technique, the different components are separated by the differential migration of solute between two phases a stationary phase and a mobile phase. Here, the principle of separation is adsorption and the stationary phase acts as an adsorbent. Depending on the particular type of stationary phase, its preparation and use with different solvents, separation can be achieved on the basis of partition or a combination of partition and adsorption. Preparation of Plates 100 g of Silica gel-G was weighed and made into a homogenous suspension with 200 ml of distilled water to form aslurry. The slurry was poured into a TLC applicator, which was adjusted to 0.25 mm thickness on flat glass plate of different dimensions (10 x 2, 10 x 5, 20 x 5, 20 x 10 cm etc.). The coated plates were allowed to dry in air, followed by heating at 100 105o C for 1 hour, cooled and stored in a dry atmosphere to protect from moisture. Before using, the plates were activated by heating at 100o C for 10 minutes. Detection of Steroids / Triterpenoids and their Glycosides Solvent systems used: Ethyl acetate: Methanol : Water 81 : 11 : 8 Ethyl acetate: Methanol : Water 75 : 15 : 10 Chloroform : Methanol : Water 70 : 30 : 4 Chloroform : Methanol : Water 64 : 50 : 10 n-Butanol :Acetic acid: Water 4 : 1 : 5 (upper phase) Benzene : Ethyl acetate 90 : 10, 80 : 20, 50 : 50 Chloroform : Methanol 95 : 5, 90 : 10, 80 : 20 Ethyl acetate: Methanol 90 : 10, 80 : 20, 50 : 50 Spray Reagents: 1) Vanillin Sulphuric acid (VS) reagent Solution I : 5% ethanolic sulphuric acid Solution II : 1% ethanolic vanillin The developed TLC plate was sprayed with 10 ml of solution I, followed immediately by 5-10 ml of solution II, then heate for 5-10 minutes at 100o C under observation. steroids / triterpenoids and their glycosides give blue, blue violet or pink colored spots. 2) Vanillin Phosphoric acid (VPA) reagent Solution a: 1 gm vanillin dissolved in 100 ml of 50% phosphoric acid Solution b: 2 parts 24 % phosphoric acid and 8 parts 2% ethanolic Vanillic acid After spraying with either solution a or b, the plate was heated for 10 minutes at 100o C Red Violet colour indicates the presence of steroids / triterpenoids and their glycosides. 3) Antimony (III) chloride reagent 20% solution of antimony (III) chloride The developed TLC plate was sprayed with reagent and then heated for 5-6 minutes at 100o C Red violet color in visible light; red violet, blue and green fluorescence in UV at 365 nm indicates the presence of steroids / triterpenoids and their glycosides. 4) Anisaldehyde sulphuric acid reagent 0.5 ml of anisaldehyde was mixed with 10 ml glacial acetic acid, followed by 85 ml of methanol and 5 ml of concentrated sulphuric acid, in that order. The developed TLC plate was sprayed with reagent, heated at 100o C for 5 10 minutes. steroids / triterpenoids and their glycosides give blue, blue violet or pink coloured spots. Detection of Flavonoids and their Glycosides Solvent systems used: Chloroform : Methanol 80:20, 70:30, 50:50 Ethyl acetate : Methanol: Water 81:11:8 n- Butanol : Acetic acid : Water 4 : 1 : 5 (upper phase) Ethyl acetate: Formic acid: Glacial acetic acid: water 100:11:11:27 Ethyl acetate: Formic acid: Glacial acetic acid: Ethyl methyl ketone: Water 50:7:3:30:10 Detection The developed TLC plate was observed in visible light and in UV at 365 nm. Flavonoids and their glycosides appear as yellow, dark blue, orange zones / spots. The color gets intensified on exposure of the plates to ammonia vapors. Detection of Alkaloids Solvent systems used Benzene : Ethyl acetate : Diethylamine 6:3:1 Toluene: Ethyl acetate: Formic acid 5:4:1 Detection: Dragendorffs reagent The developed TLC plate was sprayed with reagent and then heated for 5-6 minutes at 1000C, spot will be developed.

Advancement Of Women Essay -- essays research papers

Throughout the international community, women have been a primary focus of the United Nations due to their importance to the economic and social balance in a country. The advancement of women is a vital issue concerning the world as the new millenium begins. Although the international community views women with high regard and of the utmost respect, ancient traditions, one sided beliefs, and false stereotypical propaganda, which demean and belittle women are existent in the world today. Historically, women have been victims of inequality and abusive practices, and due to this, many women never reach their full potential in the economic world. First, the primary root that hinders the progress of women is the inferiority complex at an early age. In document UN/ CRC/ 531, analyzed through UNICEF, an estimated 25% of the world’s children (developing world) are in the web of child labor. To add to this, nearly 70% of all girl/female laborers go unregistered, often performing acts of prostitution and strenuous domestic housework. This form of unregistered work is dangerous to young girls because the employers often abuse their employees sexually and physically, as well as psychologically scarring them for years. This alarming fact can be attributed to the inequality of education given to young girls. At an early age, many girls are taught to be inferior to their male counterparts, both mentally and physically. Currently, 75% of all the world’s illiterates are wom... Advancement Of Women Essay -- essays research papers Throughout the international community, women have been a primary focus of the United Nations due to their importance to the economic and social balance in a country. The advancement of women is a vital issue concerning the world as the new millenium begins. Although the international community views women with high regard and of the utmost respect, ancient traditions, one sided beliefs, and false stereotypical propaganda, which demean and belittle women are existent in the world today. Historically, women have been victims of inequality and abusive practices, and due to this, many women never reach their full potential in the economic world. First, the primary root that hinders the progress of women is the inferiority complex at an early age. In document UN/ CRC/ 531, analyzed through UNICEF, an estimated 25% of the world’s children (developing world) are in the web of child labor. To add to this, nearly 70% of all girl/female laborers go unregistered, often performing acts of prostitution and strenuous domestic housework. This form of unregistered work is dangerous to young girls because the employers often abuse their employees sexually and physically, as well as psychologically scarring them for years. This alarming fact can be attributed to the inequality of education given to young girls. At an early age, many girls are taught to be inferior to their male counterparts, both mentally and physically. Currently, 75% of all the world’s illiterates are wom...